Brain Spray Could Reverse Brain Aging

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Texas A&M Scientists have developed a nasal spray that reduces inflammation in the brain. The spray is being heralded as a potential effective treatment for dementia and Alzheimer’s patients. Research leader Dr. Ashok Shetty said, “Brain age-related diseases like dementia are a major health concern worldwide. What we’re showing is brain aging can be reversed, to help people stay mentally sharp, socially engaged and free from age-related decline.”

Scientists say they’ve reversed brain aging with a simple nasal spray www.sciencedaily.com
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Researchers at Texas A&M University say they may have found a way to do just that using a simple nasal spray designed to reduce inflammation in the brain. In a new study, scientists reported that the treatment restored memory, reduced chronic inflammation, and improved brain cell function after just two doses.

The team believes the findings could eventually lead to new therapies for conditions tied to aging and cognitive decline, including dementia and Alzheimer’s disease.

For years, scientists have known that aging brains often experience persistent low level inflammation, a process known as “neuroinflammaging.” This chronic inflammation can interfere with memory, thinking, and the brain’s ability to adapt to new situations. It is also considered a major contributor to neurodegenerative diseases.

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Now, researchers say that process may not be permanent after all.

The study was led by Dr. Ashok Shetty, university distinguished professor and associate director of the Institute for Regenerative Medicine, together with senior research scientists Dr. Madhu Leelavathi Narayana and Dr. Maheedhar Kodali. Their findings were published in the Journal of Extracellular Vesicles.

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